Association of cardiovascular disease with hospital mortality in COVID-19

Các tác giả

  • Popova Anna 1Federal State Budgetary Institution NATIONAL MEDICAL RESEARCH CENTRE OF CARDIOLOGY NAMED AFTER ACADEMICIAN E.I.CHAZOV. of the Ministry of Health of the Russian Federation
  • Pogosova Nana Federal State Budgetary Institution NATIONAL MEDICAL RESEARCH CENTRE OF CARDIOLOGY NAMED AFTER ACADEMICIAN E.I.CHAZOV. of the Ministry of Health of the Russian Federation
  • Ezhov Marat Federal State Budgetary Institution NATIONAL MEDICAL RESEARCH CENTRE OF CARDIOLOGY NAMED AFTER ACADEMICIAN E.I.CHAZOV. of the Ministry of Health of the Russian Federation
  • Barinova Irina Federal State Budgetary Institution NATIONAL MEDICAL RESEARCH CENTRE OF CARDIOLOGY NAMED AFTER ACADEMICIAN E.I.CHAZOV. of the Ministry of Health of the Russian Federation
  • Ausheva Aza Federal State Budgetary Institution NATIONAL MEDICAL RESEARCH CENTRE OF CARDIOLOGY NAMED AFTER ACADEMICIAN E.I.CHAZOV. of the Ministry of Health of the Russian Federation
  • Kuchiev David Federal State Budgetary Institution NATIONAL MEDICAL RESEARCH CENTRE OF CARDIOLOGY NAMED AFTER ACADEMICIAN E.I.CHAZOV. of the Ministry of Health of the Russian Federation
  • Arutyunov Artur Federal State Budgetary Institution NATIONAL MEDICAL RESEARCH CENTRE OF CARDIOLOGY NAMED AFTER ACADEMICIAN E.I.CHAZOV. of the Ministry of Health of the Russian Federation
  • Boytsov Sergey Federal State Budgetary Institution NATIONAL MEDICAL RESEARCH CENTRE OF CARDIOLOGY NAMED AFTER ACADEMICIAN E.I.CHAZOV. of the Ministry of Health of the Russian Federation

Tóm tắt

Background

Coronavirus disease 2019 (COVID-19) had been associated with high rates of morbidity. A number of risk factors have been identified to have a potential impact on increasing  risk of death in patients hospitalized for COVID-19. The purpose of our study was to evaluate the relationship of hospital mortality with history of cardiovascular disease (CVD) in according to Russian register of patients hospitalized for COVID-19.

Methods

758 consecutive patients with COVID-19 (403 men, the median age was 61 [18 to 95] years) were included in the study. Predictors of hospital mortality were evaluated using univariate and multivariate regression analysis, using SPSS Statistics version 23.0.

Results

During hospitalization, 59 (7.8%) patients with COVID-19 died, 677 (89.3%) were discharged and 22 (2.9%) were transferred to other hospitals. Univariate regression analysis showed that increasing of age was associated with 92% higher mortality risk for each decade (relative risk (RR) 1.92; 95% confidence interval (CI) 1.58–2.34; p<0.001). The bigger number of CVDs was associated with higher risk of death (RR 1.71; 95% CI 1.42–2.07; p<0.001). Presence of one or more CVDs, as well as atrial fibrillation, chronic heart failure (CHF), coronary heart disease, myocardial infarction, stroke history, and diabetes were associated with a higher risk of deaths during the hospitalization for COVID-19. Presence of any CVD was associated with a 3.2-fold higher risk of hospital mortality. However, this association lost its significance after adjustment for age and gender, and only CHF was associated with a 3-fold increased risk of death (RR 3.16; 95% CI 1.64–6.09; p<0.001). One more independent predictor of mortality was age (RR 1.05; 95% CI 1.03–1.08; p<0.001).

Conclusion

History of CVDs, their number and severity were associated with a higher risk of death in patients hospitalized for COVID-19. Age and CHF were independent predictors of hospital mortality.

Đã Xuất bản

08-04-2024

Cách trích dẫn

Anna, P., Nana, P., Marat, E., Irina, B., Aza, A., David, K., Artur, A., & Sergey, B. (2024). Association of cardiovascular disease with hospital mortality in COVID-19. Tạp Chí Tim mạch học Việt Nam, (104S). Truy vấn từ http://jvc.vnha.org.vn/tmh/article/view/752

Số

Số 104S (2023)

Chuyên mục

TÓM TẮT

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